The movie begins with a peeper (Jon Lovitz) sitting in a tree spying on a single mom. He gets caught out by her son who in turn fires his slingshot at the guy who falls off the tree and then dies. He ends up in Hell as what he was doing is a sin. Also in Hell, it is the 10,000th year as the current Satan's rule of Hell. He brings his three sons—Adrian, Cassius, and Nicky—to decide who will succeed him as "Prince of Darkness". Adrian and Cassius constantly torment Nicky for being their father's personal favorite, even going as far as taking control of his mind and hitting him in the face with a shovel (resulting in a slacked jaw and a speech impediment). The Devil decides to rule another 10,000 years himself because there is more to being Satan than torturing sinful souls as much as keeping the balance between good and evil, saying that none of the sons are ready to take on that responsibility. This greatly angers Adrian and Cassius, so they decide to go to Earth and create a "New Hell" there, corrupting as many souls as possible so that when they kill the souls they will have an army of Damned Souls. They escape Hell and freeze the entrance, the Fire Gate, on the way out. When no new souls can get in, Satan begins to decompose. Satan sends Nicky to Earth with a silver flask that traps the drinker inside it forever. The only way to un-freeze the gate is to get Adrian and Cassius to return through the Fire Gate inside the flask.

Nicky goes to Earth and appears in the subway at Grand Central Terminal and meets "Mr. Beefy", a talking bulldog that is "an old friend" of Satan. He says that Adrian and Cassius can possess mortals so they will be hard to find. Nicky manages to get an apartment with Todd, a failed actor. Meanwhile, Adrian (possessing a powerful Deacon) and Cassius (possessing the Mayor of New York City) corrupt an entire mass, thus taking the first steps towards New Hell. Cassius makes the mayor even change the city's slogan to "I Love Hookers" and lower the legal drinking age to 10.
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